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Bcl2 antibody, Bcl-2抗體

 
編 號 PR-1237
產(chǎn)品名稱(chēng) Bcl2 antibody, Bcl-2抗體
規 格 0.2ml
價(jià) 格 1980元
應 用 IHC,WB,ELISA,ICC,IP,IF
品 牌 Hopebiot

詳細信息: 說(shuō)明書(shū)下載

Background:  The Bcl-2 gene was isolated at the chromosomal breakpoint of t(14;18)-bearing follicular B cell lymphomas.Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal.Bcl-2 appears to function in several subcellular locations yet lacks any known motifs that would confer insight into its mechanism of action.A more recently identified protein,designated Bax p21(i.e., Bcl-associated X protein), has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2.Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activty of Bcl-2.

Description: Rabbit polyclonal to Bcl2

Immunogen: KLH conjugated synthetic peptide derived from Bcl2

Specificity:  ·Reacts with Human, Mouse, Pig, Rabbit, Cow, Dog and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 26 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

·Immunocytochemistry: 1/100-200;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

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